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Cannabis topicals bind to CB2 receptors in the skin, muscles, and connective tissue at the application site — cannabinoids stay local rather than crossing into the bloodstream, so even THC-inclusive formulas typically produce zero psychoactive effects. Formulations range from 200mg CBD isolate roll-ons for daily muscle recovery through 3000mg CBD + CBG freeze rollers for chronic joint discomfort, plus Delta-8 and Delta-9 recovery balms for buyers wanting cannabinoid intensity beyond CBD alone. Menthol, arnica, and cayenne act as permeation enhancers that carry cannabinoids past the skin's outer barrier.